Deficit in hippocampal ripples does not preclude spatial memory formation in APP/PS1 mice
نویسندگان
چکیده
منابع مشابه
Awake hippocampal sharp-wave ripples support spatial memory.
The hippocampus is critical for spatial learning and memory. Hippocampal neurons in awake animals exhibit place field activity that encodes current location, as well as sharp-wave ripple (SWR) activity during which representations based on past experiences are often replayed. The relationship between these patterns of activity and the memory functions of the hippocampus is poorly understood. We...
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ژورنال
عنوان ژورنال: Scientific Reports
سال: 2019
ISSN: 2045-2322
DOI: 10.1038/s41598-019-56582-w