Defining the nociceptor transcriptome
نویسندگان
چکیده
منابع مشابه
Defining the nociceptor transcriptome
Unbiased "omics" techniques, such as next generation RNA-sequencing, can provide entirely novel insights into biological systems. However, cellular heterogeneity presents a significant barrier to analysis and interpretation of these datasets. The neurons of the dorsal root ganglia (DRG) are an important model for studies of neuronal injury, regeneration and pain. The majority of investigators u...
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متن کاملNociceptor activation and pain
This paper reviews advances in our knowledge on the physiological properties of human nociceptors and their capacity to signal pain. Conventional microneurography was used in combination with intraneural microstimulation in subjects who estimated the magnitude of pain from nociceptor stimulation. The experimental evidence favours the notion that C polymodal nociceptors can provide a peripheral ...
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ژورنال
عنوان ژورنال: Frontiers in Molecular Neuroscience
سال: 2014
ISSN: 1662-5099
DOI: 10.3389/fnmol.2014.00087