Delayed Cutaneous Hypersensitivity Reaction to Vaxzevria (ChAdOx1-S) Vaccine against SARS-CoV-2
نویسندگان
چکیده
Recently, an increasing number of cases with delayed cutaneous reaction after immunization mRNA-based vaccines against severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) have been reported. This adverse reaction, which is considered a delayed-type or T cell-mediated hypersensitivity has described for the Moderna (mRNA-1273) and Comirnaty (Pfizer/BioNTech, BNT162b2) vaccines. We describe large local in patient who received viral vector vaccine Vaxzevria (ChAdOx1-S, AstraZeneca). The time course clinical symptoms skin mRNA similar pattern that we recognized our vaccination. phenomenon not trials to knowledge first report this vector-based SARS-CoV-2 vaccine. With this, hope raise awareness about injection site reactions also occur encourage additional reporting education regarding disease 2019 (COVID-19)
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ژورنال
عنوان ژورنال: Drugs in R & D
سال: 2021
ISSN: ['1179-6901', '1174-5886']
DOI: https://doi.org/10.1007/s40268-021-00358-z