Deletion of myeloid IRS2 enhances adipose tissue sympathetic nerve function and limits obesity

Obesity and adipose tissue endocrine function

Obesity, adipose tissue function and the role of vitamin D

INTRODUCTION Obesity is not just a cosmetic problem. Pathological accumulation of body fat can cause many health problems: insulin resistance, impaired glucose tolerance, and diabetes mellitus type 2. It may also increase morbidity and mortality. Adipose tissue plays an important role in body homeostasis by producing and secreting several bioactive proteins known as adipokines: adiponectin, lep...

Hypoxia and adipose tissue function and dysfunction in obesity.

The rise in the incidence of obesity has led to a major interest in the biology of white adipose tissue. The tissue is a major endocrine and signaling organ, with adipocytes, the characteristic cell type, secreting a multiplicity of protein factors, the adipokines. Increases in the secretion of a number of adipokines occur in obesity, underpinning inflammation in white adipose tissue and the de...

Obesity, Visceral Adipose Tissue, and Cognitive Function in Childhood.

OBJECTIVES To evaluate the effects of a 9-month physical activity intervention on changes in adiposity and cognitive control based on pretrial weight status (ie, healthy weight vs obese) in children. STUDY DESIGN Participants included obese (n = 77) and matched healthy-weight (n = 77) preadolescents (8-9 years) who participated in a 9-month physical activity randomized controlled trial. Cogni...

Obesity, adipose tissue and anti-obesity drugs

Adipose tissue Adipocytokines Obesity Anti-obesity drugs