Demystifying “bad luck”: Seemingly unrelated risk factors for CLAD may be connected by a common pathway
نویسندگان
چکیده
منابع مشابه
Cancer risk is not (just) bad luck
Tomasetti and Vogelstein recently proposed that the majority of variation in cancer risk among tissues is due to “bad luck,” that is, random mutations arising during DNA replication in normal noncancerous stem cells. They generalize this finding to cancer overall, claiming that “the stochastic effects of DNA replication appear to be the major contributor to cancer in humans.” We show that this ...
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ژورنال
عنوان ژورنال: American Journal of Transplantation
سال: 2019
ISSN: 1600-6135,1600-6143
DOI: 10.1111/ajt.15741