DEPENDENCE OF THE NEUROMUSCULAR BLOCKING EFFECT OF ATRACURIUM UPON ITS DISPOSITION
نویسندگان
چکیده
منابع مشابه
The pharmacology of atracurium: a new competitive neuromuscular blocking agent.
Atracurium besylate, 2,2'-(3,11-dioxo-4,10-dioxatridecylene)-bis-[6,7-dimethoxy-1-(3,4-dimethoxy-benzyl)-2-methyl-1,2,3,4-tetrahydroisoquinolinium] dibenzenesulphonate, is one of a new series of competitive neuromuscular blocking agents. An i.v. dose of 0.25 mg kg-1 produced complete paralysis in anaesthetized cats, dogs and rhesus monkeys; paralysis was of medium duration and was readily antag...
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Effect of ionized calcium on the neuromuscular blocking actions of atracurium and vecuronium in the cat.
We have determined neuromuscular blocking effects of atracurium and vecuronium at normal, high and low plasma concentrations of ionized calcium ( [Ca2+] ) in the cat. Twitch responses were measured bilaterally in the anterior tibialis muscles, using intact central innervation in one preparation. Plateaus of high and low [Ca2+] were created by infusions of calcium chloride and citrate, respectiv...
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ژورنال
عنوان ژورنال: British Journal of Anaesthesia
سال: 1992
ISSN: 0007-0912
DOI: 10.1093/bja/68.6.555