Depth of Interaction and Coincidence Time Resolution Characterization of Ultrahigh Resolution Time-of-Flight Prism-PET Modules

Depth-of-interaction (DOI) positron emission tomography (PET) detector with time-of-flight (TOF) readout has been developed in recent years. With DOI, PET scanner could achieve high spatial resolution and sensitivity simultaneously. improved TOF readout, better coincidence time (CTR) is achieved, making the localization of events along lines response (LORs) more accurate enhancing reconstructed image quality. Prism-PET a novel DOI-TOF module single-ended readout. It utilizes segmented prismatoid light guide array for enhanced localized sharing aims to solve tradeoff among resolution, sensitivity, cost. In this work, we characterized DOI CTR performance our module. Unprecedented resolutions 2.57 mm full width at half maximum (FWHM) 4.01 FWHM were achieved 4-to-1 9-to-1 crystal-to-pixel coupled modules, respectively, outperforming that uniform glass (5.72 FWHM). Estimated after correction 254 ps 267 respectively.