Design, Characterization, Analytical HPLC Method Validation, and Stability Studies of Racecadotril Capsules

development and validation of a new hplc analytical method for the quality control of clindamycin capsules

Development and Validation of a Stability-Indicating RP-HPLC Method for Analysis of Racecadotril in Pharmaceutical Dosage Forms

A simple stability-indicating RP-HPLC method has been developed and validated for the determination of Racecadotril (RAC) in pharmaceutical dosage forms. The mobile phase consisting of methanol and tetra butyl ammonium hydrogen sulphate (80: 20, v/v) was used using isocratic elution with UV detection at 230 nm. The method showed good linearity for RAC in the 5-120 μg/mL range being the square o...

Stability Indicating HPLC Method Development and Validation

High performance liquid chromatography (HPLC) is an integral analytical tool in assessing drug product stability. HPLC methods should be able to separate, detect, and quantify the various drug-related degradants that can form on storage or manufacturing, plus detect and quantify any drug-related impurities that may be introduced during synthesis. Forced degradation studies of new chemical entit...

Stability Indicating Analytical Method Development and Validation of Lafutidine in Tablet Dosage Form by Rp- Hplc

Objectives: To perform stability indicating analytical method development and validation of Lafutidine in tablet dosage form by reverse phase HPLC method. Materials and Methods: The method was developed employing isocratic RP-HPLC and validated for assay of Lafutidine in tablet dosage form. The method employs the use of a UV detector. Results: The developed assay method was found to be accurate...

Development and Validation of HPLC Method for the Determination of Pregabalin in Capsules

A simple, precise, specific, and accurate reverse phase HPLC method has been developed for the determination of pregabalin in capsule dosage form. The chromatography was set on Hypersil BDS, C8, 150×4.6 mm, 5 μm column using photodiode array detector. The mobile phase consisting of phosphate buffer pH 6.9 and acetonitrile in the ratio of 95:05 with flow rate of 1 ml/min. The method was validate...