منابع مشابه
Design patterns for library optimization
We apply the notion of design patterns to optimizations performed by designers of software libraries, focusing especially on object-oriented numerical libraries. We formalize three design patterns that we have abstracted from many existing libraries and discuss the role of these formalizations as a tool for guiding compiler optimizers. These optimizers operate at a very high level that would ot...
متن کاملA Library of Optimization Algorithms for Organizational Design
This paper presents a library of algorithms to solve a broad range of optimization problems arising in the normative design of organizations to execute a specific mission. The use of specific optimization algorithms for different phases of the design process leads to an efficient matching between the mission structure and that of an organization and its resources/constraints. This library of al...
متن کاملPICCOLO: a tool for combinatorial library design via multicriterion optimization.
Combinatorial library design is by nature a multicriterion problem. These criteria often include reagent diversity, product similarity to lead compounds and product novelty with respect to a corporate compound bank. More recently, developability and druglikeness have also attracted much attention in library design practices. To address this multicriterion design problem, we have developed a com...
متن کاملBayesOpt: a Bayesian optimization library for nonlinear optimization, experimental design and bandits
BayesOpt is a library with state-of-the-art Bayesian optimization methods to solve nonlinear optimization, stochastic bandits or sequential experimental design problems. Bayesian optimization characterized for being sample efficient as it builds a posterior distribution to capture the evidence and prior knowledge of the target function. Built in standard C++, the library is extremely efficient ...
متن کاملChallenges to Design and Develop of DNA Aptamers for Protein Targets. I. Optimization of Asymmetric PCR for Generation of a Single Stranded DNA Library
Aptamers, or single stranded oligonucleotides, are produced by systematic evolution of ligands by exponential enrichment, abbreviated as SELEX. In the amplification and regeneration step of SELEX technique, dsDNA is conversed to ssDNA. Asymmetric PCR is one of the methods used for the generation of ssDNA. The purpose of this study was to design a random DNA library for selection of aptamers wit...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Scientific Programming
سال: 2003
ISSN: 1058-9244,1875-919X
DOI: 10.1155/2003/382319