Design Studies of an Epithermal Neutron Beam for Neutron Capture Therapy at the Musashi Reactor
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چکیده
منابع مشابه
Optimization of the epithermal neutron beam for Boron Neutron Capture Therapy at the Brookhaven Medical Research Reactor.
The use of epithermal neutron beam in clinical trials of Boron Neutron Capture Therapy for patients with malignant brain tumors had been carried out for half a decade at the Brookhaven's Medical Reactor. The decision to permanently close this reactor in 2000 cut short the efforts to implement a new conceptual design to optimize this beam in preparation for use with possible new BNCT protocols. ...
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BNCT is a radiotherapy modality based on the neutron capture and fission reactions that occur when boron-10 is irradiated by thermal neutrons. This reaction generates alpha and lithium that produce high density of ionizations in close to the reaction site. The concept provides high absorbed doses into the cancerous cells preserving the adjacent healthy tissues. Nowadays, the available neutron s...
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The epithermal neutron beam model of the Finnish boron neutron capture therapy (BNCT) facility (FiR 1) was created using the two-dimensional (2D) discrete ordinates transport (DORT) code. The final design of the beam was achieved using the DORT model: the optimal thickness of the neutron moderator and the length and the thickness of the bismuth collimator of the beam were calculated. The final ...
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The University of Missouri Research Reactor has designed and constructed a thermal neutron beam line for use in small animal boron neutron capture therapy (BNCT) experiments. Details of the facility have been previously reported by Brockman et al.[1] and Pozzi et al.[2]. The facility utilizes a 15.24 cm diameter beam tube that extends from the beryllium reflector to the biological shield, a dis...
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Boron neutron capture therapy (BNCT) is a form of chemically targeted radiotherapy that utilises the high neutron capture cross-section of boron-10 isotope to achieve a preferential dose increase in the tumour. The BNCT dosimetry poses a special challenge as the radiation dose absorbed by the irradiated tissues consists of several dose components with different relative biological effectiveness...
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ژورنال
عنوان ژورنال: Journal of Nuclear Science and Technology
سال: 1995
ISSN: 0022-3131,1881-1248
DOI: 10.1080/18811248.1995.9731677