Desmosome Assembly and Cell-Cell Adhesion Are Membrane Raft-dependent Processes
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چکیده
منابع مشابه
Desmosome Assembly and Disassembly Are Membrane Raft-Dependent
Strong intercellular adhesion is critical for tissues that experience mechanical stress, such as the skin and heart. Desmosomes provide adhesive strength to tissues by anchoring desmosomal cadherins of neighboring cells to the intermediate filament cytoskeleton. Alterations in assembly and disassembly compromise desmosome function and may contribute to human diseases, such as the autoimmune ski...
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Differential cell adhesion, a suggested guiding force for tissue rearrangement during embryogenesis, could be affected by desmosome frequency. A model system for studying embryonic tissue-positioning behaviour involves combining different tissues and following their rearrangements. We have previously shown that for one tissue, embryonic chick heart ventricle, direction of tissue positioning can...
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Departments of Pathology and Dermatology, Northwestern University Feinberg School of Medicine, 303 E Chicago Ave., Chicago, IL 60611 2 CELLnTEC Advanced Cell Systems AG, Länggassstr. 122, Postfach, CH-3001 Bern, Switzerland Departments of Dermatology and Cell Biology, Emory University School of Medicine, Atlanta, GA 30322 Institute of Animal Pathology, University of Bern, Länggassstr. 122, Post...
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ژورنال
عنوان ژورنال: Journal of Biological Chemistry
سال: 2011
ISSN: 0021-9258
DOI: 10.1074/jbc.m110.189464