Detection of coronary stenosis with myocardial contrast echocardiography using regadenoson, a selective adenosine A2A receptor agonist
نویسندگان
چکیده
منابع مشابه
Detection of coronary stenosis with myocardial contrast echocardiography using regadenoson, a selective adenosine A2A receptor agonist.
AIMS Regadenoson is comparable to adenosine in pharmacologic radionuclide stress tests but has not been studied with stress myocardial contrast echocardiography. This study assessed the haemodynamic profile and ability of regadenoson, a novel selective A(2A) receptor agonist, to detect coronary artery stenosis during myocardial contrast echocardiography. METHODS AND RESULTS Myocardial contras...
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Background—We investigated the hemodynamic and coronary vasodilatory effects of CGS-21680, a potent selective adenosine A2A agonist, as well as its potential use as a new stress modality in combination with perfusion scintigraphy. Methods and Results—A stenosis of the left anterior descending coronary artery (LAD) was produced in dogs to reduce the reactive hyperemic response to ,20%. Adenosine...
متن کاملComparative value of dobutamine and adenosine stress in the detection of coronary stenosis with myocardial contrast echocardiography.
BACKGROUND Controversy continues as to whether adenosine or dobutamine is the superior pharmacological stress agent for myocardial contrast echocardiography (MCE). METHODS AND RESULTS We compared real-time MCE refilling curves and wall thickening during adenosine and dobutamine stress in 14 open-chest dogs with left anterior descending and left circumflex coronary artery stenoses that reduced...
متن کاملRapid detection of coronary artery stenoses with real-time perfusion echocardiography during regadenoson stress.
BACKGROUND Real-time myocardial contrast echocardiography permits the detection of myocardial perfusion abnormalities during stress echocardiography, which may improve the accuracy of the test in detecting coronary artery stenoses. We hypothesized that this technique could be used after a bolus injection of the selective A2A receptor agonist regadenoson to rapidly and safely detect coronary art...
متن کاملRegadenoson in the detection of coronary artery disease
Myocardial perfusion studies use either physical exercise or pharmacologic vasodilator stress to induce maximum myocardial hyperemia. Adenosine and dipyridamole are the most commonly used agents to induce coronary arterial vasodilation for myocardial perfusion imaging. Both cause frequent undesirable side-effects. Because of its ultrashort half-life, adenosine must be administered by constant i...
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ژورنال
عنوان ژورنال: European Heart Journal - Cardiovascular Imaging
سال: 2011
ISSN: 2047-2404,2047-2412
DOI: 10.1093/ejechocard/jer232