Detection of trisomy 18 and trisomy 13 using first and second trimester Down's syndrome screening markers
نویسندگان
چکیده
منابع مشابه
Second-trimester screening for trisomy-21 using prefrontal space ratio.
OBJECTIVE To investigate the potential value of prefrontal space ratio (PFSR) in second-trimester screening for trisomy-21. METHODS A retrospective study utilizing stored midsagittal two-dimensional images of fetal profiles in 240 euploid and 45 trisomy-21 pregnancies at 16(+0)-23(+6) weeks' gestation. The vertical distance between the leading edge of the skull and that of the skin (D1) and t...
متن کاملFirst-trimester screening for trisomy 21 using alpha-fetoprotein.
OBJECTIVE To investigate the potential value of adding maternal serum alpha-fetoprotein (AFP) to free β-human chorionic gonadotropin (β-hCG) and PAPP-A and fetal nuchal translucency (NT) thickness in first-trimester screening for trisomy 21. METHODS In this case control study, serum AFP was measured in 100 trisomy 21 and 1,500 euploid pregnancies in which screening for trisomy 21 had been per...
متن کاملFacial profile markers in second- and third-trimester fetuses with trisomy 18.
OBJECTIVES To evaluate nasal bone length (NBL), maxilla-nasion-mandible (MNM) angle, fetal profile (FP) line, prenasal thickness (PT), prenasal thickness to nasal bone length (PT:NBL) ratio and prefrontal space ratio (PFSR) as markers of trisomy 18 in the second and third trimesters of pregnancy. METHODS The NBL, MNM angle, FP line, PT, PT:NBL ratio and PFSR were measured retrospectively from...
متن کاملMeta-analysis of second-trimester markers for trisomy 21.
OBJECTIVE To summarize by meta-analysis the accumulated data on the screening performance of second-trimester sonographic markers for fetal trisomy 21. METHODS We conducted a literature search to identify studies between 1995 and September 2012 that provided data on the incidence of sonographic markers in trisomy 21 and euploid fetuses at 14-24 weeks' gestation. Weighted independent estimates...
متن کاملSecond-trimester genetic sonography after first-trimester combined screening for trisomy 21.
OBJECTIVE The purpose of this study was to evaluate the trisomy 21 screening performance of the first-trimester combined test followed by second-trimester genetic sonography. METHODS This retrospective cohort study included all women with singleton pregnancies undergoing combined screening followed by genetic sonography at 17 to 21 weeks from January 1, 2005, to January 31, 2008. Combined tes...
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ژورنال
عنوان ژورنال: Journal of Medical Screening
سال: 2013
ISSN: 0969-1413,1475-5793
DOI: 10.1177/0969141313484904