Develompent and validation of a RP-HPLC method for simulatenous determination of terbutaline sulfate, guaifenesin, bromhexine hydrochloride and sodium benzoate in a syrup formulation
نویسندگان
چکیده
منابع مشابه
Stability-indicating HPLC Method for Simultaneous Determination of Terbutaline Sulphate, Bromhexine Hydrochloride and Guaifenesin
The aim of the present study was the development and subsequent validation of a simple, precise and stability-indicating reversed phase HPLC method for the simultaneous determination of guaifenesin, terbutaline sulphate and bromhexine hydrochloride in the presence of their potential impurities in a single run. The photolytic as well as hydrolytic impurities were detected as 3,5-dihydroxybenzoic...
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متن کاملDevelopment and validation of a fast, simple and specific stability indicating RP-HPLC method for determination of Dexpanthenol in eye gel formulation.
AIn this study a simple and reliable stability-indicating RP-HPLC method was developed and validated for analysis of Dexpanthenol in an artificial tear formulation. The chromatographic separation was performed on a HPLC C18 column (25.0 cm 4.6 mm, 5 m) using a mixture of 0.037 M monobasic potassium phosphate in water (adjusted with 0.1% (v/v) phosphoric acid to a pH of 3.2) and methanol (90:...
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ژورنال
عنوان ژورنال: Supplement 1
سال: 2020
ISSN: 1857-8969,1409-8695
DOI: 10.33320/maced.pharm.bull.2020.66.03.091