Development and validation of biomarker classifiers for treatment selection

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Development and Validation of Biomarker Classifiers for Treatment Selection.

Many syndromes traditionally viewed as individual diseases are heterogeneous in molecular pathogenesis and treatment responsiveness. This often leads to the conduct of large clinical trials to identify small average treatment benefits for heterogeneous groups of patients. Drugs that demonstrate effectiveness in such trials may subsequently be used broadly, resulting in ineffective treatment of ...

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Validation of pharmacogenomic biomarker classifiers for treatment selection.

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development and implementation of an optimized control strategy for induction machine in an electric vehicle

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ژورنال

عنوان ژورنال: Journal of Statistical Planning and Inference

سال: 2008

ISSN: 0378-3758

DOI: 10.1016/j.jspi.2007.06.010