Development of a RVFV ELISA that can distinguish infected from vaccinated animals
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چکیده
منابع مشابه
Development of a skin test for bovine tuberculosis for differentiating infected from vaccinated animals.
The tuberculin skin test has been used for the diagnosis of bovine and human tuberculosis (TB) for over a hundred years. However, the specificity of the test is compromised by vaccination with the Mycobacterium bovis-derived vaccine strain bacille Calmette-Guérin (BCG). Since current promising vaccines against bovine TB are based on heterologous prime-boost combinations that include BCG, there ...
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We have identified continuous antigenic determinants within the amino acid sequences of the conserved nonstructural region containing proteins 2C and 3ABC of foot-and-mouth disease virus which can distinguish between the sera from vaccinated and infected animals. An ELISA based on a 3B peptide gave a positive reaction with sera from cattle, pigs, sheep and guinea pigs infected with all seven se...
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Countries that are free of foot and mouth disease (FMD) are reluctant to use vaccine in the event of an outbreak because of the difficulties this can cause in re-establishing freedom from FMD status to the satisfaction of trading partners. The problem does not lie in distinguishing between vaccinated and recovered animals as vaccinated animals can be tagged or otherwise marked to show that they...
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ژورنال
عنوان ژورنال: Virology Journal
سال: 2009
ISSN: 1743-422X
DOI: 10.1186/1743-422x-6-125