Development of ethosomes with taguchi robust design-based studies for transdermal delivery of alfuzosin hydrochloride
نویسندگان
چکیده
منابع مشابه
Effect of Chemical Enhancers in Transdermal Permeation of Alfuzosin Hydrochloride
The objective of the present study is to explore the efficient chemical penetration enhancer among the various enhancers available in overcoming the stratum corneum barrier in transdermal delivery of Alfuzosin hydrochloride (AH). The different enhancers were incorporated in 2% Carbopol gel which was selected as a control and evaluated by in vitro diffusion studies through dialysis membrane and ...
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Proniosomes are well documented for transdermal drug delivery and preferred over other vesicular systems because they are biodegradable, biocompatible, non-toxic, possess skin penetration ability and prolong the release of drugs by acting as depot in deeper layers of skin. The purpose of the current study was to investigate the feasibility of proniosomes as transdermal drug delivery system for ...
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The aim of the present study was to develop and investigate the feasibility of delivering Nebivolol as a transdermal patch by iontophoresis. The passive and electrically assisted transdermal delivery of Nebivolol hydrochloride by iontophoresis will improve the therapeutic efficacy and overcome the difficulties raised in oral drug delivery. Because of its extensive hepatic metabolism and low dos...
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This study aimed to evaluate transdermal delivery of vancomycin hydrochloride using the combination of ethosomes as an encapsulating vesicle and iontophoresis. Ethosomes were prepared and evaluated in terms of electrochemical stability. Cathodal iontophoresis of negatively charged ethosomes and anodal iontophoresis of free drug solution and positively charged vesicles were conducted. The effect...
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ژورنال
عنوان ژورنال: International Current Pharmaceutical Journal
سال: 2012
ISSN: 2224-9486
DOI: 10.3329/icpj.v1i11.12063