Development of Harmaline-induced Tremor in a Swine Model

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Riluzole Ameliorates Harmaline-Induced Tremor in Rat

Introduction: Excessive olivo-cerebellar burst-firing occurs during harmaline-induced tremor. We hypothesized that antiglutamatergic agents would suppress harmaline tremor. From this point of view, the aim of current study was to investigate the effects of riluzole on harmaline-induced tremor in rat. Material and Methods: Four groups of Wistar rats weighing 80–100 g were injected with harmaline...

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Riluzole Ameliorates Harmaline-induced Tremor in Rat

INTRODUCTION Excessive olivo-cerebellar burst-firing occurs during harmaline-induced tremor. We hypothesized that antiglutamatergic agents would suppress harmaline tremor. From this point of view, the aim of the present study was to investigate the effects of riluzole on harmaline-induced tremor in rat. METHODS Four groups of Wistar rats weighing 80-100 g were injected with harmaline (30 mg/ ...

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riluzole ameliorates harmaline-induced tremor in rat

introduction: excessive olivo-cerebellar burst-firing occurs during harmaline-induced tremor. we hypothesized that antiglutamatergic agents would suppress harmaline tremor. from this point of view, the aim of current study was to investigate the effects of riluzole on harmaline-induced tremor in rat. material and methods: four groups of wistar rats weighing 80–100 g were injected with harmaline...

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Review Harmaline Tremor: Underlying Mechanisms in a Potential Animal Model of Essential Tremor

Background: Harmaline and harmine are tremorigenic b-carbolines that, on administration to experimental animals, induce an acute postural and kinetic tremor of axial and truncal musculature. This drug-induced action tremor has been proposed as a model of essential tremor. Here we review what is known about harmaline tremor. Methods: Using the terms harmaline and harmine on PubMed, we searched f...

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The effect of memantine in harmaline-induced tremor and neurodegeneration.

Essential tremor (ET) is one of the most common and most disabling movement disorders among adults. The drug treatment of ET remains unsatisfactory. Additional therapies are required for patients with inadequate response or intolerable side effects. The current study aims to investigate the anti-tremogenic and neuroprotective effects of memantine (NMDA receptor antagonist) on the harmaline mode...

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ژورنال

عنوان ژورنال: Tremor and Other Hyperkinetic Movements

سال: 2018

ISSN: 2160-8288

DOI: 10.5334/tohm.406