Development of Hydrophobic Carriers based tablets for Sustained Release of Verapamil
نویسندگان
چکیده
منابع مشابه
Development of lipid micromatrices based sustained release tablets of glipizide: suitability of stearic acid as release retardant
The objective of research was to explore the suitability of lipids like compritol 888 ATO and stearic acid as release retardant to develop sustained release (SR) tablets. The SR micromatrices of lipid (s) and glipizide were prepared (LM1- LM6) as intermediate product by fusion method and assessed for various pharmacotechnical properties. Micromatrices were formulated as SR tablets (F1-F6) by di...
متن کاملISOPTIN SR (verapamil HCl) Sustained-Release Oral Tablets
DESCRIPTION ISOPTIN SR (verapamil hydrochloride) is a calcium ion influx inhibitor (slow channel blocker or calcium ion antagonist). ISOPTIN SR is available for oral administration as light green, capsule shaped, scored, film-coated tablets containing 240 mg verapamil hydrochloride, as light pink, oval shaped, scored, film-coated tablets containing 180 mg verapamil hydrochloride, and as light v...
متن کاملDrug Transport Mechanisms from Carbopol/Eudragit Verapamil Sustained-Release Tablets
The objectives of this study were to compare dissolution profiles of a verapamil (VRP) formulation manufactured inhouse and Isoptin SR using USP Apparatus 2 and 3 and to elucidate drug release kinetics of these dosage forms. Eudragit NE 30D (ethyl acrylate–methyl methacrylate copolymer in a 2:1 ratio) aqueous dispersion was used as a granulating binder for the manufacture of VRP mini-matrix sus...
متن کاملFormulation and Evaluation of Sustained Release Matrix Tablets of Glipizide
The purpose of this study was to develop a new monolithic matrix tablet to completely deliver glipizide in a zero order manner over a sustained period. Two approaches were examined using drug in a formulation that contain polymer like hydroxylpropyl methyl-cellulose K 100 (HPMCK) and Eudragit L 100. The granules were prepared by wet granulation method and thereby formulated as F-1, F-2. F...
متن کاملdevelopment of lipid micromatrices based sustained release tablets of glipizide: suitability of stearic acid as release retardant
the objective of research was to explore the suitability of lipids like compritol 888 ato and stearic acid as release retardant to develop sustained release (sr) tablets. the sr micromatrices of lipid (s) and glipizide were prepared (lm1- lm6) as intermediate product by fusion method and assessed for various pharmacotechnical properties. micromatrices were formulated as sr tablets (f1-f6) by di...
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ژورنال
عنوان ژورنال: Journal of Applied Pharmaceutical Science
سال: 2015
ISSN: 2231-3354
DOI: 10.7324/japs.2015.501222