Development of new pharmacological test methods using human iPS cell-derived cardiomyocytes
نویسندگان
چکیده
منابع مشابه
Improvement of acquisition and analysis methods in multi-electrode array experiments with iPS cell-derived cardiomyocytes.
INTRODUCTION Multi-electrode array (MEA) systems and human induced pluripotent stem (iPS) cell-derived cardiomyocytes are frequently used to characterize the electrophysiological effects of drug candidates for the prediction of QT prolongation and proarrhythmic potential. However, the optimal experimental conditions for obtaining reliable experimental data, such as high-pass filter (HPF) freque...
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ژورنال
عنوان ژورنال: Folia Pharmacologica Japonica
سال: 2017
ISSN: 0015-5691,1347-8397
DOI: 10.1254/fpj.149.110