Development of Novel Radiopharmaceuticals to Combat Invasive Fungal Infections
نویسندگان
چکیده
منابع مشابه
Invasive Fungal Infections Secondary to Traumatic Injury.
Invasive fungal infection (IFI) is a rare but serious complication of traumatic injury. The purpose of this article is to review the epidemiology, natural history, mycology, risk factors, diagnosis, treatment, and outcomes associated with post-traumatic IFI in military and civilian populations. The epidemiology of post-traumatic IFI is poorly characterized, but incidence appears to be rising. P...
متن کاملGlucocorticoids and invasive fungal infections.
Since the 1990s, opportunistic fungal infections have emerged as a substantial cause of morbidity and mortality in profoundly immunocompromised patients. Hypercortisolaemic patients, both those with endogenous Cushing's syndrome and, much more frequently, those receiving exogenous glucocorticoid therapy, are especially at risk of such infections. This vulnerability is attributed to the complex ...
متن کاملVaccines for invasive fungal infections
Morbidity and mortality from invasive fungal infections remain unacceptably high despite availability of new antifungal agents, underscoring the need for more effective preventative strategies. Due to our enhanced understanding of the host defense and pathogenetic mechanisms that lead to invasive fungal infections, it should be feasible to develop vaccines targeting these infections. A common i...
متن کاملInvasive fungal infections in children.
The past two decades have seen a considerable increase in both frequency and importance of opportunistic invasive fungal infections in pediatric hospitals. At the same time, major advances have been made in the diagnosis of fungal diseases, the development of algorithms of antifungal interventions, and the design and implementation of pediatric clinical trials. Most importantly, several new ant...
متن کاملHistopathological techniques for the diagnosis of combat-related invasive fungal wound infections
BACKGROUND Effective management of trauma-related invasive fungal wound infections (IFIs) depends on early diagnosis and timely initiation of treatment. We evaluated the utility of routine staining, histochemical stains and frozen section for fungal element identification. METHODS A total of 383 histopathological specimens collected from 66 combat-injured United States military personnel with...
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ژورنال
عنوان ژورنال: Journal of Medical Imaging and Radiation Sciences
سال: 2019
ISSN: 1939-8654
DOI: 10.1016/j.jmir.2019.03.018