Developmental Changes in Pedunculopontine Nucleus (PPN) Neurons
نویسندگان
چکیده
منابع مشابه
Developmental changes in pedunculopontine nucleus (PPN) neurons.
The developmental decrease in rapid-eye-movement (REM) sleep in man occurs between birth and after puberty. We hypothesize that if this decrease in REM sleep does not occur, lifelong increases in REM sleep drive may ensue. Such disorders are characterized by hypervigilance and sensory-gating deficits, such as are present in postpubertal onset disorders like schizophrenia, panic attacks (a form ...
متن کاملEndocannabinoid signaling modulates neurons of the pedunculopontine nucleus (PPN) via astrocytes Endocannabinoid signaling in the PPN
Department of Physiology, Faculty of Medicine, University of Debrecen, Debrecen, Hungary „DE-MTA Lendület” Cellular Physiology Research Group of the Hungarian Academy of Sciences Department of Anatomy, Histology and Embryology; Faculty of Medicine, University of Debrecen, Debrecen, Hungary MTA-DE Neuroscience Research Group, Faculty of Medicine, University of Debrecen, Debrecen, Hungary MTA-DE-...
متن کاملEffects of pedunculopontine nucleus (PPN) stimulation on caudal pontine reticular formation (PnC) neurons in vitro.
Stimulation of the pedunculopontine nucleus (PPN) is known to induce changes in arousal and postural/locomotor states. Previously, PPN stimulation was reported to induce prolonged responses (PRs) in extracellularly recorded PnC neurons in the decerebrate cat. The present study used intracellular recordings in semihorizontal slices from rat brain stem (postnatal days 12-21) to determine response...
متن کاملAstrocyte-Dependent Slow Inward Currents (SICs) Participate in Neuromodulatory Mechanisms in the Pedunculopontine Nucleus (PPN)
Slow inward currents (SICs) are known as excitatory events of neurons caused by astrocytic glutamate release and consequential activation of neuronal extrasynaptic NMDA receptors. In the present article we investigate the role of these astrocyte-dependent excitatory events on a cholinergic nucleus of the reticular activating system (RAS), the pedunculopontine nucleus (PPN). It is well known abo...
متن کاملDeep Brain Stimulation of the Pedunculopontine Tegmental Nucleus (PPN) Influences Visual Contrast Sensitivity in Human Observers
The parapontine nucleus of the thalamus (PPN) is a neuromodulatory midbrain structure with widespread connectivity to cortical and subcortical motor structures, as well as the spinal cord. The PPN also projects to the thalamus, including visual relay nuclei like the LGN and the pulvinar. Moreover, there is intense connectivity with sensory structures of the tegmentum in particular with the supe...
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ژورنال
عنوان ژورنال: Journal of Neurophysiology
سال: 2004
ISSN: 0022-3077,1522-1598
DOI: 10.1152/jn.01024.2003