Dexamethasone combined with other antiemetics versus single antiemetics for prevention of postoperative nausea and vomiting after laparoscopic cholecystectomy: An updated systematic review and meta-analysis

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Dexamethasone combined with other antiemetics for prophylaxis after laparoscopic cholecystectomy.

BACKGROUND/OBJECTIVE Postoperative nausea and vomiting (PONV) is one of the most common and distressing adverse events after laparoscopic cholecystectomy (LC). A meta-analysis of randomized clinical trials (RCTs) was performed to determine the efficacy and safety of dexamethasone combined with other antiemetic in the prevention of PONV in patients undergoing LC. METHODS A systematic literatur...

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Comparison of dexmedetomidine and dexamethasone for prevention of postoperative nausea and vomiting after laparoscopic cholecystectomy

BACKGROUND Postoperative nausea and vomiting (PONV) are common following laparoscopic cholecystectomy (LC). Dexamethasone has been reported to reduce PONV. However, there is insufficient evidence regarding the effect of dexmedetomidine in decreasing PONV. This study was designed to compare the effects of a single dose of dexmedetomidine to dexamethasone for reducing PONV after LC. METHODS Eig...

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Combination of Antiemetics for the Prevention of Postoperative Nausea and Vomiting in High-Risk Patients

It was previously reported that the Korean predictive model could be used to identify patients at high risk of postoperative nausea and vomiting (PONV). This study investigated whether PONV in the high-risk and very high-risk patients identified by the Korean predictive model could be prevented by multiple prophylactic antiemetics. A total of 2,456 patients were selected from our previous PONV ...

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Prevention of Postoperative Nausea and Vomiting in Laparoscopic Cholecystectomy

Objective: To assess the efficacy of ondansetron and dexamethasone in the prevention of nausea and vomiting in patients undergoing laparoscopic cholecystectomy. Material and Methods: This study was conducted at the Department of Surgery, Khyber Teaching Hospital, Peshawar from May 2010 to December 2010. A total of 67 patients, aged 18 years and above, scheduled for elective cholecystectomy were...

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Dexamethasone reduces nausea and vomiting after laparoscopic cholecystectomy.

We have evaluated the antiemetic effect of i.v. dexamethasone compared with saline in the prevention of nausea and vomiting after laparoscopic cholecystectomy. We studied 90 patients requiring general anaesthesia for laparoscopic cholecystectomy, in a randomized, double-blind, placebo-controlled study. The dexamethasone group (n = 45) received dexamethasone 8 mg i.v. and the saline group receiv...

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ژورنال

عنوان ژورنال: International Journal of Surgery

سال: 2016

ISSN: 1743-9191

DOI: 10.1016/j.ijsu.2016.10.034