Dexamethasone Loaded Liposomes by Thin-Film Hydration and Microfluidic Procedures: Formulation Challenges
نویسندگان
چکیده
منابع مشابه
Formulation of mefenamic acid loaded transfersomal gel by thin film hydration technique and hand shaking method
Objective(s): The aim of present study is to formulate mefenamic acid transdermal gel based on vesicular drug delivery approaches.Materials and Methods: For the preparation of mefenamic acid transdermal gel, transfersomes were selected as colloidal carriers. Transfersomes were prepared by hand shaking and thin film hydration techniques. The obtained transfersomes were characterized for vesicula...
متن کاملApplication of response surface methodology in development of sirolimus liposomes prepared by thin film hydration technique.
Introduction : The present investigation was aimed to optimize the formulating process of sirolimus liposomes by thin film hydration method. Methods : In this study, a 3(2) factorial design method was used to investigate the influence of two independent variables in the preparation of sirolimus liposomes. The dipalmitoylphosphatidylcholine (DPPC) /Cholesterol (Chol) and dioleoyl phosphoethanola...
متن کاملFormulation and evaluation of gliclazide loaded liposomes
Diabetes is the disease caused due to deficiency of insulin. Antidiabetic drug Gliclazide decreases blood glucose level by inducing insulin. Frequent administration of Gliclazide decreases patient compliance. The present study was aimed to formulate a sustained release formulation of Gliclazide, liposomes. Due to the sustained release property of liposomes it increases patient compliance. Ethan...
متن کاملFormulation and evaluation of celastrol-loaded liposomes.
The main purpose of this study was to evaluate the intestinal absorption and the antineoplastic effect of the poorly water-soluble drug celastrol when liposomes were used as oral drug delivery system. Liposomes were prepared by the ethanol-injection method. An optimized liposome formulation composed of phospholipid, cholesterol and Tween-80 resulted in favorable encapsulation efficiency at 98.0...
متن کاملUtilization of thin film method for preparation of celecoxib loaded liposomes.
PURPOSE Celecoxib is nonsteroiddal anti-inflammatory drug that has been used extensively to treat patients with arthritis. The aim of the present study was to formulate and characterize liposomal vesicles loaded with celecoxib. METHODS Liposomes were prepared by thin film method using soya lecithin and cholesterol. The release of drug was determined using a dialysis membrane method. Liposomes...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: International Journal of Molecular Sciences
سال: 2020
ISSN: 1422-0067
DOI: 10.3390/ijms21051611