Diagnostic performance of diffusion-weighted imaging for prostate cancer: Peripheral zone versus transition zone
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چکیده
منابع مشابه
Differentiation of prostate cancer and prostatitis in the peripheral zone with diffusion-weighted imaging: ADC value versus normalized ADC value
Purpose: The purpose of this study is to compare the diagnostic accuracy of prostate apparent diffusion coefficient (ADC) versus normalized prostate ADC using the normal peripheral zone as the reference site for the differentiation of prostate cancer and prostatitis in the peripheral zone. Methods: Fifty-two patients, 32 with prostate cancer and 19 with prostatitis, were assessed with single-sh...
متن کاملMolecular differences in transition zone and peripheral zone prostate tumors.
Prostate tumors arise primarily in the peripheral zone (PZ) of the prostate, but 20-30% arise in the transition zone (TZ). Zone of origin may have prognostic value or reflect distinct molecular subtypes; however, it can be difficult to determine in practice. Using whole-genome gene expression, we built a signature of zone using normal tissue from five individuals and found that it successfully ...
متن کاملSignal Intensity of High B-value Diffusion-weighted Imaging for the Detection of Prostate Cancer
Background: Diffusion-weighted imaging (DWI) is a main component of multiparametric MRI for prostate cancer detection. Recently, high b value DWI has gained more attention because of its capability for tumor characterization. Objective: To assess based on histopathological findings of transrectal ultrasound (TRUS)-guided prostate biopsy as a reference, an...
متن کاملBiologic differences between peripheral and transition zone prostate cancer.
BACKGROUND Prostate cancer arises in the transition zone (TZ) in approximately 20-25% of cases. Modern biopsy and surveillance protocols, and advances in prostate cancer imaging, have renewed interest in TZ prostate cancers. We compared TZ and PZ prostate cancer to determine if cancer location is independently associated with better outcomes. METHODS We evaluated an expanded cohort of 1354 me...
متن کاملDifferentiation of prostate cancer lesions in the Transition Zone by diffusion-weighted MRI
OBJECTIVE To differentiate prostate cancer lesions in transition zone by diffusion-weighted-MRI (DW-MRI). METHODS Data from a total of 63 patients who underwent preoperative DWI (b of 0-1000 s/mm2) were prospectively collected and processed by a monoexponential (DWI) model and compared with a biexponential (IVIM) model for quantitation of apparent diffusion coefficients (ADCs), perfusion frac...
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ژورنال
عنوان ژورنال: PLOS ONE
سال: 2018
ISSN: 1932-6203
DOI: 10.1371/journal.pone.0199636