Diazepam or nitrazepam? A question of cost.
نویسندگان
چکیده
منابع مشابه
Quantitative determination of medazepam, diazepam, and nitrazepam in whole blood by flame-ionization gas-liquid chromatography.
Accurate methods are described for the qualitative and quantitative determination of medazepam, diazepam, and nitrazepam in 5 ml of whole blood. Medazepam and diazepam are analyzed intact and nitrazepam is chromatographed as its trimethylsilyl derivative by flame-ionization gas-chromatography on “1% OV-17.” A supplementary column of “2% OV-1” is used to separate nitrazepam TMS from diazepam whe...
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The solubility enhancement of diazepam and nitrazepam in water was analyzed depending on temperature and amount of α-cyclodextrin (α-CD), β-cyclodextrin (β-CD) and 2-hydroxypropyl-β-cyclodextrin (2-HP-β-CD). The interactions of drug-cyclodextrin in solution were investigated by the phase-solubility analysis. Diazepam (nitrazepam) content in aqueous complexation medium was analyzed UV spectropho...
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The sedative effects of nitrazepam in a dose of 5 mg and 10 mg have been compared with Mandrax, a combination of methaqualone 250 mg with diphenhydramine 25 mg. Studies were carried out in gynaecological patients undergoing minor surgical operations using the scoring system previously described. The degree of sedation obtained after administration of the two dose levels of nitrazepam was compar...
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Nitrazepam is metabolized in part by nitro-reduction to an amine followed by acetylation. This acetylation step has been shown to be under the control of the same genetic polymorphism as sulphamethazine (syn: sulphadimidine).
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BACKGROUND Rabies still poses a significant human health problem throughout most of Africa, where the majority of the human cases results from dog bites. Mass dog vaccination is considered to be the most effective method to prevent rabies in humans. Our objective was to systematically review research articles on dog rabies parenteral vaccination coverage in Africa in relation to dog accessibili...
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ژورنال
عنوان ژورنال: British Journal of Clinical Pharmacology
سال: 1977
ISSN: 0306-5251
DOI: 10.1111/j.1365-2125.1977.tb00772.x