Differences in left ventricular and left atrial function assessed during breath-holding and breathing

PurposeTo analyze differences in systolic and diastolic left ventricular (LV) as well atrial (LA) function parameters obtained from identical cardiac magnetic resonance (MR) imaging techniques during inspiratory breath-holding breathing (breath-hold to differences).Method56 subjects without signs of heart failure (23/33 male/female, age 58 ± 14 years) underwent 3 T MR cine real-time transmitral phase contrast with the same spatial temporal resolution free breathing. LV LA volumetric were derived segmentation series, peak velocities early-diastolic myocardial velocity series. Corresponding breath-hold compared by Bland-Altman analysis; repeatability measurements was quantified variance component analysis. p < 0.05 regarded statistically significant.ResultsMean between results vs. significant for (end-diastolic volume=−7 mL, = 0.002; end-systolic 0.001; ejection fraction %, rate 22 mL/s, filling rate=−34 0.025), (maximum volume=-6 total fraction=-4%, active fraction=-2%, 0.013; before contraction 0.001) (transmitral=-6 cm/s, tissue velocity=-1.8 0.001). Standard deviations breath-hold-to-breathing exceeded corresponding repeatabilities measurements.ConclusionsSystolic acquired differ, large inter-individual variations are possible. Thus, state should be taken into account, especially when comparing patient follow-up different respiratory states.