Different expression patterns of oncogenes and proto-oncogenes in hereditary and carcinogen-induced tumors of xiphophorus
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چکیده
منابع مشابه
Different expression patterns of oncogenes and proto-oncogenes in hereditary and carcinogen-induced tumors of Xiphophorus.
Hereditary melanoma in Xiphophorus hybrids carrying the melanoma-inducing Tu-Sd locus is caused by transcriptional activation of the Xmrk gene that resides at the Tu-Sd locus and encodes a novel member of receptor tyrosine kinases (RTK). In this study, a total of 27 hereditary melanomas from various hybrid genotypes harbouring 7 different Tu alleles were also found to over-express the correspon...
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15 صفحه اولExpression of retroviral sequences and oncogenes in murine hepatocellular tumors.
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متن کاملHereditary Cancer , Oncogenes , and Antioncogenes 1 Alfred
cancer; (b) agents that can change the host genome by mutagenesis or by addition or deletion of genetic material should increase this background incidence; (c) abnormalities that favor either spontaneous or induced mutations should impose an elevated risk of cancer; and (d) inheritance of an initiating muta tion should strongly predipose to cancer. Consequently, there should be 4 groups of pers...
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ژورنال
عنوان ژورنال: International Journal of Cancer
سال: 1993
ISSN: 0020-7136,1097-0215
DOI: 10.1002/ijc.2910550220