Different resting membrane potentials in posterior parietal cortex and prefrontal cortex in the view of recurrent synaptic strengths and neural network dynamics

In this study, we introduce the importance of elevated membrane potentials (MPs) in prefrontal cortex (PFC) compared to that posterior parietal (PPC), based on new observations different MP levels these areas. Through experimental data and spiking neural network modeling, investigated a possible mechanism potential PFC how physiological differences affect dynamics cognitive functions PPC PFC. Our findings indicate NMDA receptors may be main contributor region highlight using modeling toolkit investigate means by which changes synaptic properties can potentiate desirable through population activities corresponding brain regions.