Diffusion and Monod kinetics model to determine in vivo human corneal oxygen-consumption rate during soft contact lens wear
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چکیده
منابع مشابه
Diffusion and Monod kinetics model to determine in vivo human corneal oxygen-consumption rate during soft contact lens wear.
PURPOSE We present an analysis of the corneal oxygen consumption Qc from non-linear models, using data of oxygen partial pressure or tension (P(O2) ) obtained from in vivo estimation previously reported by other authors. (1) METHODS: Assuming that the cornea is a single homogeneous layer, the oxygen permeability through the cornea will be the same regardless of the type of lens that is availabl...
متن کاملAnalysis of the application of the generalized monod kinetics model to describe the human corneal oxygen-consumption rate during soft contact lens wear.
This work is an analysis of the application of the generalized Monod kinetics model describing human corneal oxygen consumption during soft contact lens wear to models previously used by Chhabra et al. (J Biomed Mater Res B Appl Biomater, 2009a;90:202-209, Optom Vis Sci 2009b;86:454-466) and Larrea and Büchler (Invest Ophthalmol Vis Sci 2009;50:1076-1080). We use oxygen tension from in vivo est...
متن کاملCorneal Biomechanical Changes Following Toric Soft Contact Lens Wear
PURPOSE To determine the effect of using toric soft contact lenses on corneal biomechanical properties. METHODS We enrolled 33 healthy patients with mean age of 23.18 ± 4.06 and minimal cylinder power of 1 D (-1.98 ± 0.808 SD) and negative history of contact lens use; keratoconic patients were excluded from the study. Toric soft contact lenses (BIOFINITY, Comfilcon A, Coopervision, Southampto...
متن کاملCorneal response to rigid contact lens wear.
Three adult rhesus monkeys were subjected to 2 and 24 hours of polymethylmethacrylate (PMMA) contact lens wear. The induced corneal changes were examined with the electron microscope. Mild epithelial oedema as well as early degenerative cell changes was present already after 2 hours' wear. Rigid lens wear for 24 hours produced more severe oedema and cell alterations together with premature cell...
متن کاملCorneal epithelial and aqueous humor acidification during in vivo contact lens wear in rabbits.
PURPOSE Based on contact lens-induced stromal acidification of the cornea, it has been suggested that the corneal epithelial and endothelial cells also become acidotic during contact lens wear. This alleged acidification may have a role in altered cell appearance and metabolism during contact lens wear. This study investigated the effects of anoxia, carbon dioxide retention, and contact lens ga...
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ژورنال
عنوان ژورنال: Journal of Optometry
سال: 2015
ISSN: 1888-4296
DOI: 10.1016/j.optom.2014.06.002