Digoxin’s Interactions with Various Drugs and A Case Report

Digoxin is a drug commonly used to achieve rate control in heart failure and atrial fibrillation with some form of arrhythmia. It shows positive inotropic effect by inhibiting the Na + / K ATPase pump myocardial cell membrane. Since digoxin narrow therapeutic range, dose range should be monitored individual regimen established, taking care plasma concentrations. Factors such as patient's age, renal dysfunction, abnormal electrolyte values, drug-drug or drug-plant interactions increase risk intoxication. Patients may present nausea vomiting intoxication ventricular arrhythmias fatal rhythm disorders. Although discontinued treatment, accompanying imbalances treated. In patients malignant arrhythmias, digoxin-specific antibodies considered treatment. this review, various that are frequently observed easily prevented discussed case report.