Direct and delayed effects of aflatoxin B1 on rat fetus
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چکیده
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The pretreatment effects of pentoxifylline on aflatoxin B1-induced oxidative damage in perfused rat liver
This study was conducted to investigate the hepatoprotective and antioxidant effects of pentoxifylline (PTX) against aflatoxin B1 (AFB1) exposure in perfused rat livers by evaluating damage marker enzymes, antioxidant defense systems (glutathione, GSH) and lipid peroxidation (malondialdehyde, MDA). Sixteen rats were divided randomly into four experimental groups: control, PTX, AFB1 and AFB1 + P...
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Effect of hypophysectomy and aflatoxin B1 on rat liver.
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The effects of aflatoxin B1 and dimethylsulfoxide on thymidine-3H uptake and mitosis in rat liver.
DNA synthesis, measured by thymidine-3H labeling of nuclei in autoradiographs, and mitosis have been studied in the livers of 148 weanling Fischer rats given a single intragastric dose of aflatoxin BI in dimethylsulfoxide and in 190 control rats given either dimethylsulfoxide, isotonic sodium chloride, or no treat ment. A marked reduction in both DNA synthesis and mitosis in the parenchyma! cel...
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ژورنال
عنوان ژورنال: Mycotoxins
سال: 1975
ISSN: 0285-1466,1881-0128
DOI: 10.2520/myco1975.1975.9