DISC1 mouse models as a tool to decipher gene-environment interactions in psychiatric disorders
نویسندگان
چکیده
منابع مشابه
DISC1 mouse models as a tool to decipher gene-environment interactions in psychiatric disorders
DISC1 was discovered in a Scottish pedigree in which a chromosomal translocation that breaks this gene segregates with psychiatric disorders, mainly depression and schizophrenia. Linkage and association studies in diverse populations support DISC1 as a susceptibility gene to a variety of neuropsychiatric disorders. Many Disc1 mouse models have been generated to study its neuronal functions. The...
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ژورنال
عنوان ژورنال: Frontiers in Behavioral Neuroscience
سال: 2013
ISSN: 1662-5153
DOI: 10.3389/fnbeh.2013.00113