Disseminated necrotizing leukoencephalopathy
نویسندگان
چکیده
منابع مشابه
Disseminated Necrotizing Leukoencephalopathy Complicating Septic Shock in an Immunocompetent Patient
Disseminated necrotizing leukoencephalopathy (DNL) is characterized by multiple microscopic foci of white matter necrosis. DNL was initially thought to be exclusively associated with immunosuppression conditions but it has been recently described in immunocompetent patients in septic shock. A 90-year-old immunocompetent woman with no previous neurological impairment presented with septic shock ...
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To the editor We report a case of disseminated necrotizing leukoencephalopathy (DNL) occurring after alemtuzumab treatment for multiple sclerosis (MS). A 33 year-old female patient with a 14-year history of highly active, relapsingremitting MS despite treatment with interferons, natalizumab and fingolimod was administered 12 mg of alemtuzumab for five consecutive days. Alemtuzumab is a humanize...
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denced a decerebrate coma with preserved brainstem reflexes. Diffuse PSWC were evident upon EEG recording ( fig. 1 ). In spite of sodium correction, valproate administration and supportive therapy, no clinical or EEG improvement was observed. The CSF 14-3-3 protein test was positive, and tau concentration was raised (5,080 pg/ml). Brain MRI showed mildly high DWI signals involving the left pari...
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Cryptococcosis is an opportunistic fungal infection caused by Crypt ococcus neoformans, an encapsulated yeast of worldwide distribution that is associated with pigeon droppings. The main route of infection is inhalation and in immunocompetent individuals it produces asymptomatic pneumonitis and can very rarely produce primary skin infection.1-3 However, in immunocompromised individuals the infe...
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Patients with disseminated cryptococcosis infrequently present with cutaneous involvement. Skin lesions, when present, are usually multiple and polymorphous in appearance. Cellulitis caused by Cryptococcus neoformans is rare, and necrotizing vasculitis associated with cryptococcal vascular invasion has not to our knowledge been reported. We report here a case of disseminated cryptococcosis in a...
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ژورنال
عنوان ژورنال: Arquivos de Neuro-Psiquiatria
سال: 2018
ISSN: 1678-4227,0004-282X
DOI: 10.1590/0004-282x20180123