Diversity of Tn1546 in vanA -positive Enterococcus faecium clinical isolates with VanA, VanB, and VanD phenotypes and susceptibility to vancomycin

VanB phenotype-vanA genotype Enterococcus faecium with heterogeneous expression

VanA and VanB Positive Vancomycin-resistant Staphylococcus aureus Among Clinical Isolates in Shiraz, South of Iran.

OBJECTIVE The purpose of this study was to determine the prevalence of vancomycin-resistant Staphylococcus aureus isolated from clinical samples in Shiraz hospitals. METHODS From March to December 2012, 100 S. aureus isolates (mainly from wound and blood) were collected from three hospitals in Shiraz, south of Iran. After identification of Staphylococcus aureus by biochemical, microbiological...

Heteroresistance to teicoplanin in Enterococcus faecium harboring the vanA gene.

Hospital-acquired infections caused by vancomycin-resistant enterococci (VRE) are increasing. The resistance of VRE to multiple antibiotics makes them clinically challenging. There are at least six phenotypes of VRE, including VanA, VanB, VanC, VanD, VanE, and VanG (2, 8). These phenotypes correspond with the genotypes vanA, vanB, vanC, vanD, vanE, and vanG. VanA and VanB phenotypes are common ...

Emergence of VanB phenotype-vanA genotype Enterococcus faecium clinical isolate in Bulgaria.

anA glycopeptide resistance is characterized by acquired nducible resistance to both vancomycin and teicoplanin, hereas the VanB phenotype is characterized by variable evels of resistance to vancomycin but susceptibility to eicoplanin.1 Here we report a vancomycin-resistant Enterooccus faecium (VREFm) strain with VanB phenotype-vanA enotype incongruence. In the course of antimicrobial susceptib...

Prevalence of vancomycin-variable Enterococcus faecium (VVE) among vanA-positive sterile site isolates and patient factors associated with VVE bacteremia

Vancomycin-variable enterococci (VVE) are vanA-positive, vancomycin-susceptible enterococci with the ability to revert to a vancomycin-resistant phenotype on exposure to vancomycin. We sought to assess the prevalence of VVE and to determine clinical characteristics of patients infected with VVE. We prospectively collected Enterococcus faecium sterile site isolates from Toronto Invasive Bacteria...