DNA Hairs Provide Potential for Molecular Self-Assembly

DNA Hairs Provide Potential for Molecular Self-Assembly

For many years, condensed-matter physicists have been involved with the fundamental problem of predicting how atoms and molecules behave collectively, exploiting their understanding for often unforeseen technological applications. More recently, the reconstruction of the atomic and molecular world on the nanoand microlength scales using human-engineered building blocks has come into focus. Nano...

-stabilized self-assembly triplex DNA molecular switch

Molecular Tiling and DNA Self-assembly

We examine hypotheses coming from the physical world and address new mathematical issues on tiling. We hope to bring to the attention of mathematicians the way that chemists use tiling in nanotechnology, where the aim is to propose building blocks and experimental protocols suitable for the construction of 1D, 2D and 3D macromolecular assembly. We shall especially concentrate on DNA nanotechnol...

Self-assembling DNA Nanostructures for Patterned Molecular Assembly

The Chapter describes the use of DNA for molecular-scale self-assembly. DNA-nanostructures provide a versatile toolbox with which to organize nanoscale materials. We begin with a discussion of DNA-nanostructures, starting with the self-assembly of various building-blocks known as DNA tiles. We describe how these can be made to self-assemble into two and threedimensional lattices. We discuss var...

DNA self-assembly for nanomedicine.

Self-assembling DNA nanostructures based on rationally designed DNA branch junction molecules has recently led to the construction of patterned supramolecular structures with increased complexities. An intrinsic value of DNA tiles and patterns lies in their utility as molecular pegboard for deterministic positioning of molecules or particles with accurate distance and architectural control. Thi...