DNA topology in chromatin is defined by nucleosome spacing
نویسندگان
چکیده
منابع مشابه
DNA topology in chromatin is defined by nucleosome spacing
In eukaryotic nucleosomes, DNA makes ~1.7 superhelical turns around histone octamer. However, there is a long-standing discrepancy between the nucleosome core structure determined by x-ray crystallography and measurements of DNA topology in circular minichromosomes, indicating that there is only ~1.0 superhelical turn per nucleosome. Although several theoretical assumptions were put forward to ...
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ژورنال
عنوان ژورنال: Science Advances
سال: 2017
ISSN: 2375-2548
DOI: 10.1126/sciadv.1700957