Do we measure what matters to patients and why?

Molecular approaches to diagnosis of invasive aspergillosis what we know and what we do not know.

Invasive aspergillosis (IA) are a major complication in immunocompromized patients where can be serious and rapidly fatal. Early diagnosis and early appropriate antifungal treatment is important in reducing mortality and morbidity. But despite many efforts to develop detection methods, the diagnosis of IA still remains challenging and current conventional methods are limited for adequate diagno...

Diagnostic and therapeutic challenges for dermatologists: What shall we do when we don’t know what to do?

What shall we do when we have done everything we could for the diagnosis and treatment of a patient, but were not successful? What shall we do when there is no definite treatment for a patient? What shall we do when we have no diagnosis or treatment for a patient? Some useful suggestions are presented here to get rid of these situations.

Do We Know What We Do not Know? A Response to Celine Bonnet

Indicators: It Matters What We Measure

James R. Karr, University of Washington Humans measure things to understand the past, to document the present, and sometimes to predict the future. But humans neither measure everything nor measure things at random. Industrialized humans measure some things because they give pleasure—batting averages of favorite baseball players, for instance—and they measure other things because they are assum...

Why do we like what we like? When information flow matters

1 Wellcome Laboratory of Neurobiology, University College London, London, UK 2 The Italian Society for Neuroaesthetics ‘Semir Zeki’, Trieste, Italy 3 Laboratoire de Neurosciences Fonctionnelles et Pathologies (EA 4559), Université Lille-Nord de France, Lille, France 4 Hôpital de la Pitié-Salpêtrière, Paris, France 5 Centre de Neuro-imagerie de Recherche, Paris, France 6 Centre de Recherche de l...