Does pulmonary metastasectomy of colorectal metastases translate to better survival? A systematic review

ABSTRACT Introduction: Surgical resection of the primary and metastatic tumour is increasingly recommended in suitable patients with colorectal cancer (CRC). While role metastasectomy well studied established liver metastasis, evidence remains limited pulmonary metastases. This systematic review was conducted to examine current on lung (LUM) CRC. Methods: Three databases were systematically searched, identify studies that compared survival outcomes LUM, factors affected decision for LUM. Results: From a total 5,477 records, 6 eventually identified. Two papers reported findings from one randomised controlled trial 4 retrospective reviews. There no clear benefit who underwent LUM those did not. When against metastasectomy, there also benefit. Patients more likely have single tumour, metachronous disease. Conclusion: The suggests but by inherent selection bias reviews, clinical performed not completed. More prospective are required understand true effect Keywords: Colorectal cancer, metastases,