Downsizing tumour therapeutics

Downsizing 1 Downsizing Effects on Survivors: Layoffs, Offshoring & Outsourcing

In a representative sample of 13,683 U.S. employees, we compared survivors of layoffs, offshoring, outsourcing, and their combinations to a group who experienced no downsizing. Survivors of layoffs perceived lower organizational performance, job security, affective attachment, calculative attachment, and had higher turnover intentions than the comparison. Offshoring survivors perceived lower pe...

Employee Morale during Downsizing

Tumour radiobiology beyond fractionation

Historically it has been shown repeatedly that single high doses of radiation do not allow a therapeutic differential between tumor and critical normal tissues but dose fractionation does. The purpose of conventional dose fractionation is to increase dose to the tumor while preserving normal tissue function. Tumors are generally irradiated with 2Gy dose per fraction delivered daily to a more or...

Surviving Defense Downsizing

Six years after Congress began reducing defense outlays, small California machine shops and aircraft parts suppliers remain highly dependent on the aerospace industry. Many firms in these two segments of the state's small defense aerospace supplier base have not branched into production of cutting-edge products for commercial customers. And other firms in these segments also may face shortages ...

Efficient Public Sector Downsizing

Most downsizing operations exhibit high financial returns, but their economic returns crucially depend on their design. After briefly comparing public sector employment across countries, this paper analyzes the optimal design of downsizing operations from a microeconomic perspective. It first discusses how to identify redundant workers when individual productivity is observable, as is often the...