Doxycycline-Induced Photo-onycholysis

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Photo-onycholysis: two cases induced by doxycycline.

Photo-onycholysis is a phototoxic reaction, which is usually drug-induced. It consists of the separation of the nail from the nail bed due to ultraviolet radiation. We report two cases of female patients who developed distal onycholysis while receiving doxycycline. Among the drugs that cause photo-onycholysis, the most frequently cited are tetracyclines, psoralens and fluoroquinolones. Photo-on...

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Diclofenac-Induced Photo-Onycholysis.

Onycholysis is the detachment of the nail plate from the nail bed. If drug-induced, it can be an isolated phenomenon, but it may also accompany or follow a cutaneous phototoxicity reaction due to drug intake and exposure to ultraviolet irradiation. Photo-onycholysis is a rare photosensitivity reaction due to exposure to either a natural or artificial source of light. Many drugs are responsible ...

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Photo-onycholysis associated with the use of doxycycline.

The Netherlands Pharmacovigilance Centre Lareb received five reports concerning photo-onycholysis associated with the use of doxycycline (table). All five patients used 200 mg of doxycycline a day for the prophylactic treatment of Lyme disease after tick bite. In all cases the affected nails had been exposed to the sun during the summer. All patients showed (partial) recovery after several mont...

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DOXYCYCLINE-INDUCED ESOPHAGEAL ULCER

During a period of 4 years (1983-1986), we have seen 18 patients with esophageal ulcer following the intake of doxycycline capsules at the University Hospitals of Shiraz Medical School. During the same period only one other patient with a drug-induced esophageal ulcer was seen and this was found to be due to a mefenemic acid capsule. Diagnosis was made by esophagoscopy and after two weeks,...

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Esophageal Ulcereation Induced by Doxycycline

We have observed esophageal ulceration in 15 patients who have been taking doxycycline (Vibromycin) for URI and GU infections. The most usual symptom was retrosternal pain, burning sensation and odynophagia, which sometimes referred to their back and shoulder Symptoms usually occured 5-10 days after their treatment. Endoscopy revealed shallow ulcerations in middle third of esophagus, biopsy sho...

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ژورنال

عنوان ژورنال: Journal of Travel Medicine

سال: 2006

ISSN: 1195-1982

DOI: 10.2310/7060.2004.19210