Drug–target interaction prediction: databases, web servers and computational models
نویسندگان
چکیده
منابع مشابه
Web Servers , Databases , and Algorithms for the Analysis of Protein Interaction Networks
Understanding the cell as a system has become one of the foremost challenges in the post-genomic era. As a result of advances in high-throughput (HTP) methodologies, we have seen a rapid growth in new types of data at the whole-genome scale. Over the last decade, HTP experimental techniques such as yeast two-hybrid assays and co-affinity purification couple with mass spectrometry have generated...
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Although tools for managing Web-based information are primitive, the number of institutions using the Web as an information system continues to grow rapidly. The World Wide Web has become a world-wide information system in spite of the lack of features common to most information systems. Many of the tools used to manage Web-based information utilize either a database or a proxy HTTP server to o...
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The combination of computational and directed evolution methods has proven a winning strategy for protein engineering. We refer to this approach as computer-aided protein directed evolution (CAPDE) and the review summarizes the recent developments in this rapidly growing field. We will restrict ourselves to overview the availability, usability and limitations of web servers, databases and other...
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ژورنال
عنوان ژورنال: Briefings in Bioinformatics
سال: 2015
ISSN: 1467-5463,1477-4054
DOI: 10.1093/bib/bbv066