Duration of Bisphosphonate Treatment
نویسندگان
چکیده
منابع مشابه
Renal complications from bisphosphonate treatment.
PURPOSE OF REVIEW More than 10 years ago evidence emerged that bisphosphonate therapy especially in malignant bone diseases is associated with renal complications. The nature of renal injury from bisphosphonates has become clearer in recent years. RECENT FINDINGS Pamidronate can rarely cause (collapsing) focal segmental glomerular sclerosis with the nephrotic syndrome and renal insufficiency....
متن کاملBisphosphonate treatment recommendations for oncologists.
Renal safety is an important consideration for oncologists who are treating patients with bisphosphonates. In recent years, there has been increasing awareness about the development of bisphosphonate-induced nephrotoxicity. This has emerged mainly from increased clinical experience with zoledronic acid (Zometa); Novartis Pharmaceuticals Corporation, East Hanover, NJ, http://www.pharma.us.novart...
متن کاملRECENT ADVANCES Bisphosphonate treatment of bone disease
MECHANISM OF ACTION AND RELATIVE POTENCY Bisphosphonates are chemical analogues of pyrophosphate. The presence of a carbon rather than oxygen atom at the centre of the molecule prevents its breakdown. The two phosphonate groups are attached directly to the carbon atom from which also extend the R1 and R2 side chains (fig 1). The R1 side chain is usually a hydroxyl group and is often referred to...
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ژورنال
عنوان ژورنال: Korean Journal of Medicine
سال: 2014
ISSN: 1738-9364,2289-0769
DOI: 10.3904/kjm.2014.87.2.151