Dynamic Modeling of Apoptosis and its Interaction with Cell Growth in Mammalian Cell Culture

نویسندگان
چکیده

برای دانلود رایگان متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید

اگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید

منابع مشابه

P.oleracea induced apoptosis and inhibited the cell growth in oral epithelial cancer cell line

Despite the progress in cancer therapies such as chemotherapy and radiation, its eradication remains as unattainable dream for the patients and doctors. Recently, using supplementary agents such as herbal medicine with fewer side effects seems efficient and attractive. Therefore, the purpose of the present study is to investigate if the ethanolic extract of P.oleracea has cytotoxicity and apopt...

متن کامل

CircRNA_0109291 regulates cell growth and migration in oral squamous cell carcinoma and its clinical significance

Objective(s): Circular RNAs (circRNAs), a new class of non-coding RNAs, have emerged as important regulators during tumorigenesis. However, the functions of circRNAs have not been completely clarified in the progression of cancers. In our study, a novel circRNA hsa_circ_0109291 was investigated in oral squamous cell carcinoma (OSCC) tissues and cell lines. Materials and Methods: The expression ...

متن کامل

Overexpression of MiR-138 Inhibits Cell Growth and Induces Caspase-mediated Apoptosis in Acute Promyelocytic Leukemia Cell Line

Dysregulated expression of miRNAs can play a vital role in pathogenesis of leukemia. The shortened telomere length, and elevated telomerase activity in acute promyelocytic leukemia cells are mainly indicative of extensive proliferative activity. This study aimed to investigate the effect of overexpression of miR-138 on telomerase activity, and cell proliferation of acute promyelocytic leukemia ...

متن کامل

Using the Microcyte flow cytometer to monitor cell number, viability, and apoptosis in mammalian cell culture.

The Microcyte is a novel, portable flow cytometer based on diode laser technology whose use has been established for yeast and bacterial analysis. We present data that demonstrate its suitability for routine mammalian cell counting and viability determination. To extend its range of applications in the field of animal cell culture biotechnology, a test to determine the number of apoptotic cells...

متن کامل

Establishment of synthetic growth media for mammalian cell culture.

Eagle showed that a medium containing the 13 amino acids and the seven vitamins found to be essential for the growth of L and HeLa cells, each at the optimum concentration and appropriately supplemented with glucose, does not permit growth unless a small amount of serum was added (Eagle, 1973). Therefore it has been suggested that serum contains macromolecular factors required for multiplicatio...

متن کامل

ذخیره در منابع من


  با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید

ژورنال

عنوان ژورنال: IFAC Proceedings Volumes

سال: 2011

ISSN: 1474-6670

DOI: 10.3182/20110828-6-it-1002.02462