Dynamics of Various Phospholipase C-B Complexes
نویسندگان
چکیده
منابع مشابه
Structural Insights into Phospholipase C-b Function
Phospholipase C (PLC) enzymes convert phosphatidylinositol4,5-bisphosphate into the second messengers diacylglycerol and inositol-1,4,5-triphosphate. The production of these molecules promotes the release of intracellular calcium and activation of protein kinase C, which results in profound cellular changes. The PLCb subfamily is of particular interest given its prominent role in cardiovascular...
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ژورنال
عنوان ژورنال: Biophysical Journal
سال: 2017
ISSN: 0006-3495
DOI: 10.1016/j.bpj.2016.11.526