E3 ligase SAUL1 serves as a positive regulator of PAMP‐triggered immunity and its homeostasis is monitored by immune receptor SOC3
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چکیده
منابع مشابه
An E3 ligase possessing an iron-responsive hemerythrin domain is a regulator of iron homeostasis.
Cellular iron homeostasis is maintained by the coordinate posttranscriptional regulation of genes responsible for iron uptake, release, use, and storage through the actions of the iron regulatory proteins IRP1 and IRP2. However, the manner in which iron levels are sensed to affect IRP2 activity is poorly understood. We found that an E3 ubiquitin ligase complex containing the FBXL5 protein targe...
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Chao Luo, Xiao-Teng Cai, Jin Du, Tao-Lan Zhao, Peng-Fei Wang, Ping-Xia Zhao, Rui Liu, Qi Xie, Xiao-Feng Cao, and Cheng-Bin Xiang School of Life Sciences, University of Science and Technology of China, Hefei, Anhui Province 230027, China State Key Laboratory of Plant Genomics and National Center for Plant Gene Research, Institute of Genetics and Developmental Biology, Chinese Academy of Science,...
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Identification of positive regulators of T-cell immunity induced during autoimmune diseases is critical for developing novel therapies. The endoplasmic reticulum resident ubiquitin ligase Hrd1 has recently emerged as a critical regulator of dendritic cell antigen presentation, but its role in T-cell immunity is unknown. Here we show that genetic deletion of Hrd1 in mice inhibits T-cell prolifer...
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The level and activity of the forkhead family transcription factor FOXP3 determine the immune function of FOXP3+Tregs. At the beginning of infectious processes, FOXP3+Tregs may regulate effector immune cell responses and lead to failure to control infection. FOXP3+Tregs may also help to limit collateral tissue damage when the antiviral immune responses are too vigorous. Understanding the regula...
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ژورنال
عنوان ژورنال: New Phytologist
سال: 2017
ISSN: 0028-646X,1469-8137
DOI: 10.1111/nph.14678