Early adversity and combat exposure interact to influence anterior cingulate cortex volume in combat veterans

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Early adversity and combat exposure interact to influence anterior cingulate cortex volume in combat veterans☆

OBJECTIVE Childhood and combat trauma have been observed to interact to influence amygdala volume in a sample of U.S. military veterans with and without PTSD. This interaction was assessed in a second, functionally-related fear system component, the pregenual and dorsal anterior cingulate cortex, using the same sample and modeling approach. METHOD Anterior cingulate cortical tissues (gray + w...

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Right anterior cingulate cortical volume covaries with respiratory sinus arrhythmia magnitude in combat veterans.

Existing data suggest anterior cingulate cortex (ACC) plays a role in autonomic regulation. In persons with posttraumatic stress disorder (PTSD), autonomic regulation appears impaired and smaller mean ACC volume has been reported. This study examined relationships between ACC volume and the magnitude of respiratory sinus arrhythmia (RSA) in 77 U.S. combat veterans at rest, 40 of whom met criter...

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Combat veterans with comorbid PTSD and mild TBI exhibit a greater inhibitory processing ERP from the dorsal anterior cingulate cortex.

Posttraumatic stress disorder (PTSD) is common among combat personnel with mild traumatic brain injury (mTBI). While patients with either PTSD or mTBI share abnormal activation of multiple frontal brain areas, anterior cingulate cortex (ACC) activity during inhibitory processing may be particularly affected by PTSD. To further test this hypothesis, we recorded electroencephalography from 32 com...

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Hippocampal volume, PTSD, and alcoholism in combat veterans.

Studies imposing rigorous control over lifetime alcohol intake have usually not found smaller hippocampal volumes in persons with posttraumatic stress disorder. Because the majority of negative studies have used adolescent samples, it has been suggested that chronicity is a necessary condition for such findings. To test the hypothesis that a smaller hippocampus in PTSD is unrelated to comorbid ...

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Documented combat exposure of US veterans seeking treatment for combat-related post-traumatic stress disorder.

BACKGROUND There are concerns regarding the validity of combat exposure reports of veterans seeking treatment for combat-related post-traumatic stress disorder (PTSD) within US Veterans Affairs Medical Centers. AIMS To verify combat exposure history for a relevant sample through objective historical data. METHOD Archival records were reviewed from the US National Military Personnel Records ...

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ژورنال

عنوان ژورنال: NeuroImage: Clinical

سال: 2013

ISSN: 2213-1582

DOI: 10.1016/j.nicl.2013.04.016