Early Identification of Acute Traumatic Coagulopathy Using Clinical Prediction Tools: A Systematic Review

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Acute traumatic coagulopathy.

PURPOSE OF REVIEW Recent therapeutic and observational studies have demonstrated improved survival with better management of haemostasis early after injury. This review delineates our current understanding of the clinical importance, aetiology and pathophysiology of acute traumatic coagulopathy (ATC). RECENT FINDINGS Trauma causes an acute disruption of the equilibrium between all components ...

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Acute traumatic coagulopathy.

PURPOSE OF REVIEW Mortality from trauma remains a global public health challenge, with most preventable deaths due to bleeding. The recognition of acute traumatic coagulopathy as a distinct clinical entity characterized by early coagulation dysfunction, arising prior to medical intervention, has revolutionized trauma management over the last decade. The aim of this article is to review our curr...

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Pathogenesis of acute traumatic coagulopathy.

Acute traumatic coagulopathy (ATC) is an early endogenous process, driven by the combination of tissue injury and shock that is associated with increased mortality and worse outcomes in the polytrauma patient. This review summarizes our current understanding of the pathophysiology of ATC and the role of rapid diagnostics in the management of severe trauma hemorrhage. In particular we consider d...

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Acute Traumatic Coagulopathy: an Endogenous Precursor of Trauma-induced Coagulopathy

Recent findings Trauma causes an acute disruption of the equilibrium between all components of haemostasis (coagulation, anticoagulation, fibrinolysis, platelets and endothelium). In patients with a combination of severe tissue damage and systemic hypoperfusion, this will progress rapidly to an endogenous coagulopathy that is independently associated with worse outcomes. New discoveries of the ...

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Non-traumatic Causes of Brown-Sequard Syndrome: A Case Series and Clinical Update with Systematic Review.

Background: Brown-Sequard syndrome (BSS) is a rare neurological condition resulting from a hemisection injury to or unilateral compression on the spinal cord. The most common causes of BSS that are amenable to be treated surgically can be divided into traumatic and non-traumatic injuries. Traumatic injuries are often reported as the main cause of BSS. However, non-traumatic injuries of the spin...

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ژورنال

عنوان ژورنال: Medicina

سال: 2019

ISSN: 1648-9144

DOI: 10.3390/medicina55100653