Effect of Interferon-τ Administration on Endometrium of Nonpregnant Ewes: A Comparison with Pregnant Ewes
نویسندگان
چکیده
منابع مشابه
Effect of interferon-tau administration on endometrium of nonpregnant ewes: a comparison with pregnant ewes.
In ruminants, conceptus interferon-tau (IFNT) alters maternal physiology to accommodate a pregnancy. We hypothesized that the effectiveness of IFNT on extending corpus luteum (CL) life span in nonpregnant ewes would depend upon the dose and manner of administration and would be correlated with the response in gene expression in endometrium. We anticipated that IFNT, whether administered im or b...
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During pregnancy, plasma ACTH and cortisol are chronically increased; this appears to occur through a reset of hypothalamo-pituitary-adrenal (HPA) activity. We have hypothesized that differences in mineralocorticoid receptor activity in pregnancy may alter feedback inhibition of the HPA axis. We tested the effect of MR antagonism in pregnant and nonpregnant ewes infused for 4 h with saline or t...
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The antiluteolytic effect of prostaglandin (PG) E2 was tested in two experiments. In experiment I, seven nonpregnant ewes that had ovulated bilaterally, were laparotomized on day-11 postestrus. Uterine horns were isolated by ligatures between the internal and external bifurcations and around blood vessels in the intercornual area. An Alzet TM minipump (25 • 6.5 ram) containing PGE2 (delivery ra...
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The effects of 1) a rapid intravenous injection of insulin (4.4 IU), 2) a continuous intravenous infusion of insulin (.14 IU/min), or 3) a rapid intravenous injection of glucose (.24 g/kg body weight) into nonpregnant ewes and 4) a continuous intravenous infusion of glucose (1.2 mg/kg body weight/rain) into pregnant ewes on plasma amino acid metabolism and a-amino acid nitrogen (~-NH 2 -N) upta...
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ژورنال
عنوان ژورنال: Endocrinology
سال: 2006
ISSN: 0013-7227,1945-7170
DOI: 10.1210/en.2005-1310