Effect of Mild Stress in Mice Leatently Infected Pseudorabies Virus

Effects of mild stress on the immune response against pseudorabies virus in mice.

Stress is a recognised problem in intensive pig husbandry, which might lead to changes in immune reactivity. To study the effect of stress on the development of an anti-viral immune response, we used a murine model in which mice were immunized with an attenuated strain of pseudorabies virus (PRV). The effect of two stress treatments, both relevant to intensive pig husbandry, on the development ...

Quantitative whole-cell proteome analysis of pseudorabies virus-infected cells.

A quantitative proteome study using the stable isotope labeling with amino acids in cell culture technique was performed on bovine kidney cells after infection with the alphaherpesvirus pseudorabies virus (PrV), the etiological agent of Aujeszky's disease. To enhance yields of proteins to be identified, raw extracts were fractionated by affinity solid-phase extraction with a combination of a ci...

Neuroinvasion and Lethality in Mice Two Modes of Pseudorabies Virus

Pseudorabies Virus

Etiology • Pseudorabies virus (PRV) is an enveloped, double-stranded DNA virus belonging to the family Herpesviridae. Also known as suid herpesvirus-1 (SuHV-1), the virus causes Aujeszky’s disease. • ‘Classical’ PRV strains affecting multiple species were first isolated in the early 1900s. ‘Variant’ PRV strains emerged in swine in China in 2011. • Genomic sequencing and phylogenetic analyses ha...

Pseudorabies Virus

Etiology • Pseudorabies virus (PRV) is an enveloped, double-stranded DNA virus belonging to the family Herpesviridae. Also known as suid herpesvirus-1 (SuHV-1), the virus causes Aujeszky’s disease. • ‘Classical’ PRV strains affecting multiple species were first isolated in the early 1900s. ‘Variant’ PRV strains emerged in swine in China in 2011. • Genomic sequencing and phylogenetic analyses ha...